Biotechnological
applications of penicillin acylases:
state-of-the-art
strains with enhanced constitutive production of penicillin acylases, as well as on cloning and ..... Arroyo M, Torres-Guzmµn R, de la Mata I, Castillón MP, Acebal C .... maturation of penicillin amidase from E. coli. Biochim Biophys ...
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Improved
A. faecalis Penicillin Amidase Mutant Retains the
...
Abstract Penicillin amidase from Alacaligenes faecalis is an attractive biocatalyst for hydrolysis of ... found wide applications in the industrial production of ..... Arroyo M, de la Mata I, Acebal C, Pilar Castillon M (2003) Appl ...
http://www.springerlink.com/index/t91846102465u035.pdf
Production
of Penicillin Acylase
several research investigators have independently de- ... isolated by La'szlo Nyiri. Conditions of cultivation. Cultures were grown in 500-ml ..... penicillin amidase. Nature 187:237-238. HALPERN, Y. S. 1962. Induction and repression of ...
http://aem.asm.org/cgi/reprint/12/3/185.pdf
GENETIC
MODIFICATION OF THE PENIICILLIN G ACYLASE SURFACE TO 1 ...
Industriales CSIC, C/Juan de la Cierva 3, 28006 Madrid, Spain ...... penicillin amidase production. Biotechnology Progress 21:432-438. ...
http://aem.asm.org/cgi/reprint/AEM.02107-06v1.pdf
THE KINETIC
MECHANISM OF PENICILLIN V ACYLASE FROM
STREPTOMYCES ...
G and penicillin V acylases are used industrially in the production of 6-APA, the ..... Arroyo, M., Torres, R., de la Mata. I., Castillh, M.P. and Acebal, ... D.E. (1 993) “A colorimetric assay for penicillin V amidase”, Anal. Biochem. ...
http://www.informaworld.com/index/793300041.pdf
Biocatalysis and
Biotransformation
Modelling ethanol production from cellulose: separate hydrolysis and .... Kinetic and microstructural characterization of immobilized penicillin acylase from Streptomyces ... D. Hormigo, I. de la Mata, M.P. Castillón, C. Acebal & M. Arroyo. Erratum ... Substrate interaction with recombinant amidase from Pseudomonas ...
http://www.informaworld.com/index/917221069.pdf
Redalyc.
Shake flask studies for the production of
penicillin G ...
de la Mata, M. P. Castillón and C. Acebal. 2000. Optimization of 6-aminopenicillanic acid (6-APA) production by using a new immobilized penicillin acylase. ...
http://redalyc.uaemex.mx/redalyc/pdf/685/68520202.pdf
High-level
production penicillin G acylase from Alcaligenes
...
by S Cheng - 2007 - Cited by 3
http://www.aseanbiotechnology.info/Abstract/21024336.pdf
Optimization
of culture conditions for a synthetic gene expression ...
by LMTP Maldonado - 2007 - Cited by 9
http://www.aseanbiotechnology.info/Abstract/21029834.pdf
USING A
MEDIUM OF FREE AMINO ACIDS TO PRODUCE PENICILLIN G
ACYLASE ...
by RG Silva - 2006 - Cited by 8
http://www.scielo.br/pdf/bjce/v23n1/29896.pdf
MAINTENANCE OF
PENICILLIN G ACYLASE EXPRESSION BY B. megaterium
...
Arroyo, M., de la Mata, L., Acebal, C. and Pilar ... Production of Penicillin Acylase from Bacillus ... Improved Penicillin Amidase Production Using a ...
http://www.scielo.br/pdf/bjce/v24n3/a01v24n3.pdf
Differentiation
of Arnidase and 8-Lactamase by Infrared Absorption
Penicillin amidase from coliforms: its extraction. HOLT, R. J. & STEWART, G. T. (1964b). Production of amidase and P-lactamase by bacteria. ...
http://mic.sgmjournals.org/cgi/reprint/36/2/215.pdf
The
Measurement of the Liberation of Penicillinase from Bacillus
...
penicillin-amidase activity present which might theoretically give misleadingly high .... Production and liberation of penicillin-induced penicillinase by cells of Bacillus ..... de la pknicillinase de Baciltus cereus. C.R. Acad. ...
http://mic.sgmjournals.org/cgi/reprint/26/2/239.pdf
Optimization and
Scaling up of Penicillin Acylase
Production ...
by SI IDO - 2009 - Related articles
http://www.idosi.org/wasj/wasj6(10)/7.pdf
The realm
of penicillin G acylase in ك-lactam
antibiotics
by AK Chandel - 2008 - Cited by 10
http://www.ucm.es/info/btg/personales/jvsgago/1297c.pdf
Studies on
Microbial Penicillin Amidase
lly for the purpose of the 6-APA production to minimize the degradation of ... Cole (1969b) found that E. coli enzyme system was specific for L-a-amino acids. .... Abstract : Penicillin amidase of Escherichia coli was purified abot 3200 ...
http://www.jbmb.or.kr/jbmbonline/14_3/02600249.pdf
Nature and Extent of Penicillin Side-reactions,
with Particular ...
by O IDS0E - Cited by 312
http://whqlibdoc.who.int/bulletin/1968/Vol38/Vol38-No2/bulletin_1968_38(2)_159-188.pdf
PENICILLIN IN THE TREATMENT OF SYPHILIS
Les publications de l'Organisation mondiale de la Santé bénéficient de la protection prévue par les .... logical method of penicillin V production. In 1958 ...... amidase-producing strains of T. pallidum. There is ...
http://whqlibdoc.who.int/bulletin/1972/Vol47/supplement/bulletin_1972_47(supp).pdf
A novel penicillin acylase from the environmental
gene pool with ...
by EM Gabor - 2005 - Cited by 11
http://gbb.eldoc.ub.rug.nl/FILES/root/2005/EnzMicTechGabor/2005EnzMicrobTechnolGabor.pdf
Saturation mutagenesis reveals the importance of residues αR145
...
by SAW Jager - 2008 - Cited by 2
http://gbb.eldoc.ub.rug.nl/FILES/root/2008/JBiotechnolJager/2008JBiotechnolJager.pdf
Chaperone-Mediated Folding and Maturation of the
Penicillin ...
by Y Xu - 2005 - Cited by 14
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1265976/pdf/0619-05.pdf
Cloning and Characterization of the Bile Salt Hydrolase Genes (bsh
...
by GB Kim - 2004 - Cited by 21
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC520925/pdf/2412-03.pdf
The PaaX
Repressor, a Link between Penicillin G Acylase and
the ...
used for the industrial production of PAC. The PA induction .... and CICYT-P4 [Optimización de la producción de cefalosporina]). REFERENCES ... isolation and kinetics of immobilised penicillin amidases from Escherichia coli. Biochim. ...
http://jb.asm.org/cgi/reprint/186/7/2215.pdf
Molecular
Cloning, Sequence Analysis, and Characterization of a ...
alanine amidase and penicillin-resistant DD-carboxypeptidase, respectively. ... of pBluescript II SK(J) (Stratagene, La Jolla, Calif.) (Fig. 1). .... required for production of a vancomycin-inducible D,D-carboxypeptidase in .... 39. van der Linden, M. P. G., L. de Haan, O. Dideberg, and W. Keck. 1994. ...
http://jb.asm.org/cgi/reprint/181/15/4696.pdf
acid.
penicillins, spiramycin, and fusidic penicillin G,
four semi ...
lactamase nor to acylase (amidase: English, McBride, and Huang, 1960), the mechanism ... penicillinase production primarily responsible for resistance to benzylpenicillin ..... a celui de la penicilline sur les souches qui avaient ete ...
http://sti.bmj.com/content/44/2/140.full.pdf
1
Introduction to Enzyme Technology
During the 1960s, enzyme production gained speed only in modest proportions, ... 6-Aminopenicillanic acid (6-APA) penicillin amidase immobilized ..... Payen, A., Persoz, J.F., Mémoire sur la diastase, les principaux produits de ses ...
http://www.wiley-vch.de/books/sample/3527304975_c01.pdf
m te
by DY Ryu - 1973 - Related articles
http://www.cheric.org/PDF/HHKH/HK11/HK11-3-0174.pdf
References 127 REFERENCES
Arroy, M., de la Mata, I., Acebal, C. and ... (1998) Penicillin acylase in the industrial production of β-lactam antibiotics. Org. Process Research Develop., 2, ... and properties of penicillin amidase from. Bacillus megaterium. ...
http://dissertations.ub.rug.nl/FILES/faculties/science/2004/j.j.polderman.tijmes/referenc.pdf
References
Industrial production of beta-lactam antibiotics. Applied ... Arroyo, M., de la Mata, I., Acebal, C. & Castillon, M.P. (2003). Biotechnological ..... substrate specificities from penicillin amidase of Escherichia coli. Applied ...
http://dissertations.ub.rug.nl/FILES/faculties/science/2004/l.g.otten/referenc.pdf
STUDIES
ON THE CATALYSIS AND POST TRANSLATIONAL PROCESSING OF ...
posttranslational bottlenecks in the production of penicillin amidase in ...... Torres-Bacete, J., Arroyo, M., Torres-Guzmán, R., de la Mata, I., Castillón, ...
http://dspace.ncl.res.in/dspace/bitstream/2048/412/3/th1446.pdf
SYNTHETIC
POLYMER BASED AFFINITY MATRICES: SEPARATION OF ...
W. L. Sederel and G. J. De Jong, J. Appl. Polym. Sci., 17, 2835 (1973). ..... The crude penicillin G acylase enzyme (penicillin amidase or penicillin ...... has been taken for the production of single-size (monodisperse) polymer ...... L. A. Eriquez and R. F. D'Amato, Antimicrob. Agents Chemother., 15, 229. (1979). ...
http://dspace.ncl.res.in/dspace/bitstream/2048/155/1/th1315.pdf
Biocatalysis
11 Jul 2009 ... penicillin amidase. 7-aminocephalosporanic glutaryl amidase acid aspartame thermolysin ... L-aspartate-β-de- carboxylase further applications: baby foods, brewing industry, ... used for the production of R-phenylethanol by DSM ... cl o pi d og re l (P la vi x) produced by DSM Chemie Linz, ...
http://www.scripps.edu/chem/baran/images/grpmtgpdf/Gulder_Jul_09.pdf
A Search
for Peptide Ligase: Cosolvent-Mediated Conversion of ...
by CF Barbas - 1988 - Cited by 29
http://www.scripps.edu/mb/barbas/pdf/Barbas88JACS.pdf
2.7. Units
The production, isolation, and processing of commercial products require careful .... Penicillin amidase or penicillin acylase cleaves the side chain of ..... development. The chief tetracyclines are listed under structure la. ...
http://phoenix.tuwien.ac.at/lectures/pharma/Übersicht_Antibiotika.pdf
The Penicillin-Binding Proteins: Structure and
Role in ...
by E Sauvage - 2008 - Cited by 61
http://digital.csic.es/bitstream/10261/4779/1/Ayala_FemsMicroRev_234.pdf
Brazilian
Journal of Chemical Engineering
by HCT Cardias - 1999 - Cited by 9
http://digital.csic.es/bitstream/10261/2172/1/Cardias et al.pdf
Penicillinase
from Microorganisms Isolated from Soft Cheeses. I ...
crococcal production of penicillinase has been ..... type of penieillinase (fl-lactamase or penicillin amidase) formed by microorganisms of the flora of soft cheeses. ... chemique de la Penicillinase de Bacillus cereus. C. R. Acad. ...
http://jds.fass.org/cgi/reprint/52/8/1202.pdf
JOURNAL
MUIR, L. A., 1046. MULDOON, P. J., 858; 944*;. 987*. MULLER, L. D., 979*. MUNSON, A., 954* ..... De Laval, 1525. Distinguished Service, 1527. ]tonor, 1528. Pfizer-Paul Lewis, 1524 ... penicillin amidase, 938 size, 215 repeat, 778 selection, 1680 ...... acid production, 28 acidified, 834 aroma bacteria, 339 ...
http://jds.fass.org/cgi/issue_pdf/backmatter_pdf/51/12.pdf
Recueil Review
by VHM Elferink - 1991 - Related articles
http://alexandria.tue.nl/repository/freearticles/621136.pdf
CRP - ICGEB RESEARCH GRANTS AWARDED 1988-2007
Production of biodegradable-biocompatable microspheres and their use for induction of .... DE LA FUENTE GARCIA Jose. 1993. Studies of growth control in fish. .... Bacterial heterodimeric penicillin G amidases in Saccharomyces cerevisiae ...
http://www.mincyt.gov.ar/coopinter_archivos/multilateral/becas_otorgadas.pdf
Production and secretion of recombinant proteins
using Bacillus ...
the production of several enzymes such as amylases, penicillin amidase, and ...... Sarath, G., De la Motte, R. S. & Wagner, F. W. (1989). ...
http://bib1lp1.rz.tu-bs.de/docportal/servlets/MCRFileNodeServlet/DocPortal_derivate_00004176/Yang_Dissertation.pdf?hosts=local
Tying up
the loose ends: circular permutation decreases the ...
21 Jul 2009 ... A recurring problem in production of recombinant proteins is proteolysis of the full-length recombinant ... co-solvents, including penicillin amidase for the industrially ..... Nossal,N.G. and Heppel,L.A. (1966) J. Biol. ... Pedersen,J.S., Otzen,D.E. and Kristensen,P. (2002) J. Mol. Biol., 323, ...
http://peds.oxfordjournals.org/cgi/reprint/22/10/607.pdf
APPLIED AND
ENVIRONMENTAL MICROBIOLOGY
Production of Penicillin Amidase in Recombinant. Escherichia coli strains ... Maurilio De Felice. Ki Jun Jeong and Sang Yup Lee. 869-877. 894-900. 933-937. 980-986. 1129-1135 ... L. A. DeMaria, J. M. Moffet, and. D. G. Korich ...
http://www.lib.buu.ac.th/jweb/AppEnv/v69n2.pdf
Amoxicillin/clavulanate
for infections in infants
adding an amidase to the medium capable of removing the side chain from various penicillins, ...... penicillin V and beta-lactamase production of Branhamella catarrhalis. ... Varón E, Levy C, De La Rocque F, et al. Impact of antimicro- ...
http://pdfs.journals.lww.com/pidj/2003/08001/00005.pdf
A Nonpancreatic Source of the Proteolytic-enzyme
Amidase and ...
found that neomycin, tetracycline, penicillin and sul- phonamide instilled into the blind duodenal loop at ... The production of experi- mental hemorrhagic pancreatitis appears usually to be ..... normaux et de chiens porteurs d'une fistule d'Eck à des ... Donaldson LA, Joffe SN, Mcintosh W, Brodie MJ. Amylase ...
http://pdfs.journals.lww.com/annalsofsurgery/1980/02000/A_Nonpancreatic_Source_of_the_Proteolytic_enzyme.10.pdf
OPTIMIZATION OF RECOMBINATION METHODS AND EXPANDING THE UTILITY OF
...
design and the optimization of the production of PGA or of the products of the reaction. (16,17). ..... Arroyo, M., de la Mata, I., Acebal, C. and Castillon, M.P. (2003) ... kinetics of penicillin amidase from Escherichia coli. ...
http://etd.gatech.edu/theses/available/etd-11012007-234258/unrestricted/loo_bernard_l_200712_phd.pdf
POST
PENICILLIN ANTIBIOTICS:
by E Tansey - 2000 - Cited by 4
http://eprints.ucl.ac.uk/2074/1/wit6.pdf
Human
Peptidoglycan Recognition Protein-L Is an N-Acetylmuramoyl-L
...
cient for the amidase activity of PGRP-L, although its activity (in the N-terminal ... two different pathways that induce production of antimicrobial peptides. .... cus aureus Rb grown in the presence of penicillin G and analyzed as ... siently transfected with human PGRP-L in a pcDNA.3 vector as de- ...
http://www.jbc.org/cgi/reprint/278/49/49044.pdf
Correlation
between Alterations of the Penicillin-binding
Protein ...
to penicillin G (MIC. 1 μg/ml) due to the production of a ..... amidase by HPLC and mass spectrometry. We determined the ..... Vazquez, J. A., Enriquez, A. M., De la Fuente, L., Berron, S., and Baquero, M. (1996) Eur. J. Clin. ...
http://www.jbc.org/content/278/34/31529.full.pdf
BMC
Microbiology
by C García-Estrada - 2009 - Related articles
http://www.biomedcentral.com/content/pdf/1471-2180-9-104.pdf
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