Research
Article
Key words: Lovastatin, Marine actinomycetes,. HMG Co A reductase inhibitor ..... Haghighi Screening of Lovastatin Production by. Filamentous fungi, Iran . ...
/interstitial?url=http://www.jprhc.com/files/66-74.pdf
Biosynthesis
and biotechnological production of statins by
...
new hydrolase system present in a rare actinomycete Ac- tinomadura, converting mevastatin to ... The industrial process for the production of lovastatin ...
http://www.springerlink.com/index/8hnqhmpnnywgrbhf.pdf
Bioconversion
of lovastatin to a novel statin by Amycolatopsis
sp.
production of statins by filamentous fungi and application of ... coherent taxon and a distinct actinomycete lineage: proposal of. Nocardiopsaceae fam. nov. ...
http://www.springerlink.com/index/t7572786r76p0800.pdf
Purification
and Characterization of a Lovastatin Esterase from
...
actinomycetes) and fungi, were screened. Of these, the fungus ..... simvastatin from unreacted lovastatin during the production of ...
http://aem.asm.org/cgi/reprint/63/4/1307.pdf
ACTINOMYCETES AND FUNGI ASSOCIATED WITH MARINE
INVERTEBRATES: A ...
by NA Mahyudin - 2008 - Related articles
http://ir.canterbury.ac.nz/bitstream/10092/1496/1/thesis_fulltext.pdf
PRODUCTION,
PURIFICATION AND CHARACTERIZATION OF L-ASPARAGINASE ...
by S Amena - 2010 - Related articles
http://www.scielo.br/pdf/bjm/v41n1/v41n1a25.pdf
SUBMERGED
CULTURE CONDITIONS FOR THE PRODUCTION OF MYCELIAL
...
by GRT Vieira - 2008 - Related articles
http://www.scielo.br/pdf/bjm/v39n3/arq29.pdf
ABSTRACT Title of Document: ISOLATION AND CHARACTERIZATION OF A
...
by O Peraud - 2006 - Cited by 1
http://www.lib.umd.edu/drum/bitstream/1903/4114/1/umi-umd-3904.pdf
SOLID STATE FERMENTATION AS A TOOL FOR PRODUCTION
OF THREE ...
started to produce some microbial drugs such as lovastatin and .... Since the production of TGase by actinomycetes was previously ...
http://www.omikk.bme.hu/collections/phd/Vegyeszmernoki_es_Biomernoki_Kar/2009/Nagy_Viviana/tezis_eng.pdf
Effect of Butyrolactone I on the Producing Fungus, Aspergillus
...
by TG Schimmel - 1998 - Cited by 14
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC106526/pdf/am003707.pdf
REVIEW
ARTICLE Secondary Metabolites Production by
Solid-State ...
the relative production of the high producing strains ranged from 0.4 to 4 times more in SSF. In studies, with other SM like lovastatin we have found that a ...
http://www.usm.my/mjm/issues/vol1no1/vol1_review1.pdf
E 발효 및 대사산물
Screening of Edible Mushrooms for the Production of Lovastatin and Evaluation on Their HMG ... New Secondary Metabolites from a Marine Actinomycetes sp. ...
http://mbel.kaist.ac.kr/lab/news/2005/39-42.pdf
Aug 00
113-160
by G Turner - Cited by 1
http://www.sgm.ac.uk/pubs/micro_today/pdf/080004.pdf
antibacterial activity of sponge associated
by OK Radjasa - 2007 - Related articles
http://www.akademik.unsri.ac.id/download/journal/files/coastdev/antibacterial activity of sponge associated-oaj-unsri.pdf
Expression of
a Functional Fungal Polyketide Synthase in the ...
yields for actinomycete polyketide production in the plasmid expression system in CH999. ... quence analysis of lovastatin PKS from Aspergillus terreus has ...
http://jb.asm.org/cgi/reprint/177/15/4544.pdf
International
Journal of Pharmacy and Pharmaceutical Sciences
fungi, yeast, bacteria and actinomycetes; however, enzyme from fungal and ..... nutrient parameter for lovastatin production by ...
http://www.ijppsjournal.com/Vol2Issue1/287.pdf
THEOBALD SMITH
SOCIETY
16 Jun 2009 ... Actinomycetes; Classification of Micromonospora strains by rDNA and ... He designed, built and operated a pilot plant for the production and ...
http://users.tellurian.com/tss/June PICNIC09.pdf
Medium optimization for the production of
avermectin B1a by ...
by H Gao - 2009 - Cited by 4
http://www.im.ac.cn/UserFiles/File/2009/200905/bioresource tech-medium-zhanglx.PDF
PRODUCTION OF LYSINE BY LACTOBACILLI OR
ASPERGILLUS FICUUM
by D Besic - Related articles
http://library2.usask.ca/theses/available/etd-09122008-143541/unrestricted/besic_d.pdf
ANTICANDIDAL DRUGS
However actinomycetes and fungi are screened by all organizations that are involved in natural ...... of lovastatin production by filamentous fungi. J Iran. ...
http://dspace.thapar.edu:8080/dspace/bitstream/123456789/242/1/92210.pdf
Inhibition of protein famesyltransf erase: a possible mechanism of
...
blocked by lovastatin. Interestingly, significant inhibition was observed at concentrations ..... (1993) Cortisol production rate and the urinary excretion of 17- .... produced by an actinomycete. / Antibiotics, 46, 222-228. 35. KohlJM. ...
http://carcin.oxfordjournals.org/cgi/reprint/15/11/2649.pdf
Cancer
chemoprevention: principles and prospects
lovastatin limonene antisense oligonucleotides staurosporine threo-dihydrosphingosine sarcophytol A ... well, by increasing the production of activated metabolites at ...... from Actinomycetes. Cancer Res., 32, 1725-1728. 93. Nomura. ...
http://carcin.oxfordjournals.org/cgi/reprint/14/9/1737.pdf
DOI:
10.1126/science.1168243 , 161 (2009); 325 Science et al ...
10 Jul 2009 ... actinomycetes and display activity in screens; this activity masks interesting new antimicro- .... chain of the cholesterol-lowering agent lovastatin ... main is directed evolution to increase production by the chimera. ...
http://sciencemag.org/cgi/reprint/325/5937/161.pdf
DOI:
10.1126/science.287.5453.640 , 640 (2000); 287 Science et al
...
actinomycete Streptomyces coelicolor produced epothilones A and B. Strep- tomyces coelicolor is more amenable to strain improvement .... served in the PKSs for lovastatin, fumonisin, ... lone gene cluster, and production of epothilone, ...
http://www.sciencemag.org/cgi/reprint/287/5453/640.pdf
DOI: 10.1126/science.1168243 ,
161 (2009); 325 Science et al ...
of analogs for optimal activity, and production of the target drug. Biological resources. Traditionally, soil bacte- ria (especially actinomycetes), fungi, ...
http://dahuang.dhxy.info/161.pdf
SHIVAJI UNIVERSITY, KOLHAPUR
Actinomycetes: General characteristics and outline classification . Unit- VI ..... metabolites and their applications in health care – Lovastatin, Daunorubicin .... Isolation of psychrotrophic bacteria and detection of lipase production ...
http://shahu.unishivaji.ac.in/syllabus/science/MSc/M.Sc.T & D Microbiology/M.Sc. Microbiology Regular.pdf
PII: S0734-9750(00)00049-5
production processes are being replaced by microbial fermentations. ..... olites were characterized from actinomycetes alone (Sanglier et al., 1996). ...
http://www.iugaza.edu.ps/emp/emp_folders/1613/small_bugs,_big_business[1]._The_economic_power_of_the_microbe.pdf
Microbial drug discovery: 80 years of progress
by AL Demain - 2009 - Cited by 14
http://www.drew.edu/uploadedFiles/depts/Research_Institute_for_Scientists_Emeriti/ja200816a.pdf
Bacteria
production; Production of beta-lactamase SHV-18 (Antimicrob. Agents Chemother. .... Produces lovastatin (Indian J. Microbiol. 44, 133-134, 2004). (Medium 44, 30oC) ... 5124 Nocardiopsis dassonvillei. 5142 Actinomycete isolate.
http://www.ncl-india.org/ncim/catalogpdf/Supplement for addition & deletion.pdf
CHAPTER 7
ADDITIONAL MEDICINAL PROPERTIES
Mevinolin (lovastatin) produced commercially from the filamentous fungus ... redistributing cholesterol in favour of HLDL, reduced production of VLDL and LDL .... low yield of products derived from them compared with the Actinomycetes ...
http://www.icnet.uk/labs/med_mush/final_pdfs/chapt8.pdf
DOI: 10.1126/science.282.5386.63 , 63 (1998); 282 Science et al
...
by DE Cane - 1998 - Cited by 364
http://students.washington.edu/mthensel/Pabio551/Reading Assignments/Lect18 Cane etal.pdf
Marine biotechnology: An overview
applications from the production of life saving drugs to better food and conservation of organic .... tetracycline, lovastatin and resveratrol18. Polyketide ...
http://nopr.niscair.res.in/bitstream/123456789/7759/1/IJBT 5(3) 263-268.pdf
BioMicroWorld2009
CONFERENCE PROGRAM OUTLINE
A Lovastatin Production Model Possessing Features for Process Control Applications ... by nanoliter-scale cultivation of single actinomycetes spores in a ...
http://formatex.org/biomicroworld2009/files/FinalProgram.pdf
Derwent
Drug File
actinomycetes, streptomycetes and Rickettsiales. * More Specific GRAM-NEG. GRAM-POS. ..... production of compounds (especially antibiotics) by ...... LOVASTATIN. LU-224332. LY-290181. LY-290293. LY-295427. M+B-30227. M+B-31426. MCI-196 ...
http://science.thomsonreuters.com/m/pdfs/mgr/ddf_thesaurus3.pdf
Construction
of a citrinin gene cluster expression system in ...
by K Sakai - Related articles
http://www.aspergillus.org.uk/secure/articles/pdfs2/19111642.pdf
Developing
Aspergillus as a host for heterologous expression
by D Lubertozzi - 2008 - Related articles
http://www.aspergillus.org.uk/secure/articles/pdfs2/18840517.pdf
Style specifications thesis
by A Pohanka - 2006 - Cited by 1
http://diss-epsilon.slu.se/archive/00001121/01/Thesis_2006_47.pdf
The Role of Natural Product
Chemistry in Drug Discovery†
by MS Butler - 2004 - Cited by 162
http://esa.ipb.pt/pdf/Refmush_3.pdf
PII:
S1074-5521(00)00068-5
by I Fujii - 2001 - Cited by 59
http://www.ibmb.uni.wroc.pl/prace2/praca10.pdf
π WILEY-VCH-Verlag GmbH, 69451 Weinheim, Germany, 2002 1439-4227
...
by HD Mootz - Cited by 142
http://www.fil.univ-lille1.fr/FORMATIONS/DESSBIOINFO/Projet2_03/arnaud_cathelin/NRPS_fichiers/pdf/ChemBioChem2002.pdf
RSC_COFI_Ch001 1..17
of soil microorganisms, the Actinomycetes (e.g. Streptomycetes), which are ..... Commercial methods for the microbiological production of ..... studies on 6-methylsalicylic acid synthase and lovastatin polyketide synthase ...
http://www.rsc.org/ebooks/archive/free/BK9780854041367/BK9780854041367-00001.pdf
PII: S1074-5521(00)00064-8
tide synthases obtained from the actinomycetes. In part .... tants for disruption of lovastatin production [23]. Mutants ...
http://www.chm.bris.ac.uk/org/RJCox/old webpage stuff/C+B2001.pdf
WCBSURC 2007 Abstracts
has been shown that production of this hormone not only has systemic ..... Actinomycetes that are non-Frankia members have previously been isolated from the ...
http://myweb.lmu.edu/kdahlqui/wcbsurc2007/WCBSURC2007Abstracts.pdf
Genetic
Contributions to Understanding Polyketide Synthases
by DA Hopwood - 1997 - Cited by 429
http://bioinformatika.pbf.hr/Articles/Hopwood 1997.pdf
-Lactams
as Neuroprotective Agents
amentous fungi, actinomycetes and unicellular bacteria. The ..... mission is increased body temperature and heat production,. i.e., hyperthermia [25, 26]. ..... nation, specifically, gemfibrozil and lovastatin. Pharmacotherapy, ...
http://www.bentham.org/cmcaia/sample/cmcaia8-1/0004Y.pdf
No Job Name
by MS Butler - 2004 - Cited by 161
http://www.dqi.ufms.br/~lp4/JNPdrugdiscovery.pdf
CONSTRUCTING
POLYKETIDES: From Collie
by R Bentley - 1999 - Cited by 52
http://journals.pasteur.ac.ir/ARmicrobiology_1999/411.pdf
DOI:
10.1126/science.282.5386.63 , 63 (1998); 282 Science et al ...
(primarily actinomycetes, bacilli, and fila- mentous fungi) are unclear, an extraordi- nary variety of pharmacological ... cineurin), and lovastatin (anti-cholesterolem- ..... approximate natural triketide production, implying that ...
http://www.scienceonline.org/cgi/reprint/282/5386/63.pdf
DOI:
10.1126/science.287.5453.640 , 640 (2000); 287 Science et al
...
17 Mar 2010 ... actinomycete Streptomyces coelicolor produced epothilones A and B. Strep- tomyces coelicolor is more amenable to .... served in the PKSs for lovastatin, fumonisin, ... lone gene cluster, and production of epothilone, ...
http://scienceonline.org/cgi/reprint/287/5453/640.pdf
Proteasome Inhibitors as Therapeutic Agents: Current and Future
...
by JG Delcros - 2003 - Cited by 30
http://perso.univ-rennes1.fr/patrick.bauchat/siteQD/pdf/Arlot-Bonnemains.pdf
1 2
